Uukuniemi virus (UUKV) belongs to the Phlebovirus genus in the family Bunyaviridae. Some members of the family are important human pathogens, e.g. Crimean-Congo hemorrhagic fever virus, hantaviruses, and Rift Valley fever virus. Uukuniemi virus is a particularly convenient model virus for studying bunyaviral packaging, budding, and structure. Like other Bunyaviridae, UUKV is an enveloped virus with a tripartite RNA genome of negative polarity.