Rickettsias are obligate intracellular parasites, pleomorphic gram-negative cocobacilli. They multiply and divide by transverse binary fusion within the host cells. they cause a disease called “Rickettsiosis” that is characterized by certain clinical manifestations, after an incubation period that lasts an average of 7 days, which include the triad fever, headache and rash. Particularly Rickettsia conorii causes Mediterranean botanical fever. It is transmitted by the bite of the Rhipicephalus sanguineus tick, which in turn acquires it from the parasitic animals, usually canids, both domestic and wild.