Rabbit Viral Hemorrhagic Disease (VHD) is a highly contagious disease caused by a Group IV ((+)ssRNA) calicivirus that affects only rabbits of the Oryctolagus cuniculus species. Transmission of RHD occurs by direct contact with an infected animal and fomites. Rabbits acquire RHD through oral, nasal or conjunctival pathways. Urine, feces and respiratory secretions may also shed the virus. Symptomatic cases of RHD will display fever, squeals, and often coma leading to death.