Hepatitis G virus (HGV) is an RNA virus belongs to the Flaviviridae family. It is mainly transmitted through exposure to contaminated blood although other routes may also exist. Patients with chronic renal failure are at high risk of acquiring HGV because they require frequent blood transfusions. HGV infection can be diagnosed by demonstrating viremia in patient sample by reverse transcriptase (RT) PCR. The coinfection of hepatitis G with hepatitis В, С or D is detected frequently.